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Migraine Q&A - What is the best medication for migraine?

There is no easy answer to this question. Migraine medications are very individual. One person might respond very well to a particular drug, yet the same drug might have no impact at all for another person. So the best drug is really the one that works for you. Up to a third of people with migraine can satisfactorily manage migraine with over-the-counter treatments such as paracetamol, codeine, ibuprofen or aspirin. Some people find that these work better if taken with an anti-nausea drug. Non-steroidal anti-inflammatory drugs are also used as a first line therapy. These may be particularly useful for those who get their attacks at around the time of their menstrual cycle. In recent years, Triptans have become the first-line medications of choice in Ireland. Statistically these medications (Sumatriptan, Almotriptan, Frovatriptan and Zolmitriptan) work in 60-80% of cases.

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